Plant primary metabolism - From basic research to crop productivity

Plant Biochemistry

The domestication of crops was a landmark in the development of human civilisation. Today, most of our food and many of our resources are derived from plants. One of the most fundamental compounds is starch. Starch is the predominant storage carbohydrate in plants and the major constituent of our staple crops (e.g. rice, maize, wheat, potato etc). Despite its importance, our understanding of how plants make and degrade this essential resource is far from complete. Our research team focuses on the metabolic pathways leading to and from starch, and the way in which they are regulated.

We use the model plant Arabidopsis thaliana as our experimental system. This allows us to exploit the complete genome sequence and the array of post-genomic facilities to make rapid progress. Our current understanding suggests that different plants make starch is essentially the same way, as the components of the pathway appears to be highly conserved, even in distantly related species. Consequently, the knowledge gained through studying Arabidopsis will be transferable to starch-producing crops and enable their future improvement. This is an essential goal as the world population approaches its predicted peak of over 9 billion.

Research topics

  • Carbohydrate metabolism

  • Starch biosynthesis and degradation

  • Photosynthesis

Interdisciplinary

  • Plant biochemistry and physiology

  • Molecular genetics

  • Genomics, proteomics, metabolomics

Contact Person

Prof. Dr. Samuel Zeeman

ETH Zurich
Institute of Agricultural Sciences
Website
szeeman-at-ethz.ch
+41 (0)44 632 82 75

eligible for PLANT FELLOWS

Recent publications

  • Title: Mutagenesis of cysteine 81 prevents dimerization of the APS1 subunit of ADP-glucose pyrophosphorylase and alters diurnal starch turnover in Arabidopsis thaliana leaves
    Author(s): Haedrich, Nadja; Hendriks, Janneke H. M.; Koetting, Oliver; et al.
    Source: PLANT JOURNAL, 70 (2): 231-242 APR 2012
    Document type: Article (Details)
  • Title: The Phosphoglucan Phosphatase Like Sex Four2 Dephosphorylates Starch at the C3-Position in Arabidopsis
    Author(s): Santelia, Diana; Koetting, Oliver; Seung, David; et al.
    Source: PLANT CELL, 23 (11): 4096-4111 NOV 2011
    Document type: Article (Details)
  • beta-Amylase-Like Proteins Function as Transcription Factors in Arabidopsis, Controlling Shoot Growth and Development
    Reinhold, H; Soyk, S; Simkova, K; et al.
    PLANT CELL 23 (4): 1391-1403 APR 2011 (Details)
  • Progress in Arabidopsis starch research and potential biotechnological applications
    Santelia, D; Zeeman, SC
    CURRENT OPINION IN BIOTECHNOLOGY 22 (2): 271-280 APR 2011 (Details)
  • Starch-binding domains in the CBM45 family - low-affinity domains from glucan, water dikinase and alpha-amylase involved in plastidial starch metabolism
    Glaring, MA; Baumann, MJ; Abou Hachem, M; et al.
    FEBS JOURNAL 278 (7): 1175-1185 APR 2011 (Details)