Cassava biotechnology research

Crop Improvement

Cassava (Manihot esculenta Crantz) is an important starchy food crop in the tropics and subtropics. Our cassava projects focus on capacity development of cassava transformation, specific gene and promoter discovery, sustainable disease resistance and quality improvement. Several routine biotechnology tools have been established for this recalcitrant tropical crop at ETH Zürich. As a member of “BioCassava Plus Consortium”, we dedicate our research to produce transgenic cassava with elevated resistance to cassava mosaic disease (CMD) and cassava brown streak disease (CBSD), enhanced protein content and improved post-harvest storage. By collaborating with international institutions, e.g. Witwatersrand University (Johannesburg, South Africa), BECA (Nairobi, Kenya), IITA-Nairobi (Nairobi, Kenya), MARI (Dar Es Salaam, Tanzania), we help transferring the technologies to regions where it is currently needed.
The cassava research group is also applying "OMICS" technologies in order to investigate several fundamental aspects of cassava biology and stress responses (i.e. root development, drought response, post-harvest physiological deterioration).

Research topics

  • Biofortification  

  • Disease resistance  

  • Drought tolerance  

  • Promoter isolations

  • Post-harvest physiological deterioration

  • Storage root development

Interdisciplinary

  • Metabolic pathway engineering  

  • Proteomics tools applied to biotic and abiotic stress resistance  

  • Elaboration of transformation protocol for recalcitrant crops  

  • Technology transfer to developing countries 

Contact Person

Dr. Hervé Vanderschuren

ETH Zurich
Institute of Agricultural Sciences
Website
hvanderschuren-at-ethz.ch
+41 (0)44 632 87 25

eligible for PLANT FELLOWS

Recent publications

  • Reference genes for reliable potyvirus quantitation in cassava and analysis of Cassava brown streak virus load in host varieties
    Moreno, Isabel; Gruissem, Wilhelm; Vanderschuren, Herve
    JOURNAL OF VIROLOGICAL METHODS, 177 (1): 49-54 OCT 2011 (Details)
  • The BioCassava Plus Program: Biofortification of Cassava for Sub-Saharan Africa
    Sayre, R; Beeching, JR; Cahoon, EB; et al.
    ANNUAL REVIEW OF PLANT BIOLOGY, VOL 62 62: 251-272 2011 (Details)
  • iTRAQ-based analysis of changes in the cassava root proteome reveals pathways associated with post-harvest physiological deterioration
    Owiti, J; Grossmann, J; Gehrig, P; et al.
    PLANT JOURNAL 67 (1): 145-156 JUL 2011 (Details)
  • Cassava: constraints to production and the transfer of biotechnology to African laboratories
    Bull, SE; Ndunguru, J; Gruissem, W; et al.
    PLANT CELL REPORTS 30 (5): 779-787 Sp. Iss. SI MAY 2011 (Details)
  • A cross-sectional study of biotechnology awareness and teaching in European high schools
    Vanderschuren, H; Heinzmann, D; Faso, C; et al.
    NEW BIOTECHNOLOGY 27 (6): 822-828 DEC 31 2010 (Details)