Epigenetics in plants

Epigenetics in Plants

Our research focuses on the transgenerational inheritance of epigenetic information in plants and on the molecular mechanisms involved in this process. In other words, we study mechanisms of the formation, maintenance and interaction of epiallelic variants at defined loci or chromosomal regions. To be inherited, epialleles not only need to preserve their identity during meiosis and the postmeiotic division of the male and/or female gametophytes but, as the plant germ-line is formed late in development from somatic cells that have undergone many mitotic divisions, the fidelity of transgenerational inheritance also relies directly on the mitotic propagation of epigenetic states. These states can often be correlated with the particular composition of epigenetic marks; however, their contribution to a particular epigenetic state and their regulatory interactions are still far from being fully understood.

Research topics

  • Epigenetics

  • Polyploidy

  • Homologous recombination

  • Stress

Interdisciplinary

  • Genomics

  • Bioinformatics

  • Structural Biology

  • In the context of the plant science web we have collaborations with U. Grossniklaus (UZH), J.P. Métraux (UNIFR) and C. Hardke (UNIL)

Contact Person

Prof. Dr. Jerzy Paszkowski

University of Geneva
Department of Botany and Plant Biology
Website
Jerzy.Paszkowski-at-unige.ch
+41 (0)22 379 30 21


Recent publications

  • Title: Loss of DNA methylation affects the recombination landscape in Arabidopsis
    Author(s): Mirouze, Marie; Lieberman-Lazarovich, Michal; Aversano, Riccardo; et al.
    Source: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 109 (15): 5880-5885 APR 10 2012
    Document type: Article (Details)
  • Title: Structural Basis of Transcriptional Gene Silencing Mediated by Arabidopsis MOM1
    Author(s): Nishimura, Taisuke; Molinard, Guillaume; Petty, Tom J.; et al.
    Source: PLOS GENETICS, 8 (2): FEB 2012
    Document type: Article (Details)
  • Ectopic Gene Expression and Organogenesis in Arabidopsis Mutants Missing BRU1 Required for Genome Maintenance
    Ohno, Yusuke; Narangajavana, Jarunya; Yamamoto, Akiko; et al.
    GENETICS, 189 (1): 83-U694 SEP 2011 (Details)
  • Epigenetic contribution to stress adaptation in plants
    Mirouze, M; Paszkowski, J
    CURRENT OPINION IN PLANT BIOLOGY 14 (3): 267-274 JUN 2011 (Details)
  • An siRNA pathway prevents transgenerational retrotransposition in plants subjected to stress
    Ito, H; Gaubert, H; Bucher, E; et al.
    NATURE 472 (7341): 115-U151 APR 7 2011 (Details)