Molecular aspects of pathogenesis in plants
Molecular Plant-Pathogen Interactions
We are interested in the molecular determinants of fungal pathogenesis and their possible interactions with elements of the innate immune response of the plant. We predict that during a compatible interaction, virulent fungal pathogens target physiological processes of the plant to their advantage. We are studying the interaction between the model plant Arabidopsis thaliana and the necrotrophic Ascomycete Botrytis cinerea.
We are also interested in the cuticle and its role in innate immunity. Breakdown products of the cuticle were shown to be potent inducers of cutinase or developmental processes in fungal pathogens. Changes in cuticular permeability lead to a rapid induction of defense responses. This is shown in several mutants with cuticular defects that result in an increase in permeability: such plants remain free of symptoms after inoculation with B. cinerea. Our efforts are currently directed at understanding how a permeable cuticle can be linked to subsequent activation of defenses.
Research topics
Molecular basis for compatible plant-pathogen interactions
The role of fungal effectors
The role of the cuticle in plant defense
Biosynthesis and action of the hormone salicylic acid
Interdisciplinary
Studies on biocontrol of plant pathogens
Response of plants to abiotic stress
