The cereal genomes: hidden treasures for evolutionary genomics and agronomy

Plant Molecular Biology

We are studying the genomes of the grass species wheat, barley and rice to analyze genome evolution in cereals. Plant genomes generally evolve much more rapidly than animal genomes and we want to understand  the underlying molecular mechanisms. These studies in evolutionary genomics have already given surprising results: for the genomic regions analyzed to date, we found complete restructuring of the intergenic regions within 1 to 3 million years, a much faster and dramatic evolution than previously assumed.

The wheat genome is very large (5x the size of the human genome) and complex. The knowledge on cereal genome structure is used in our group for the molecular isolation of agronomically important genes from wheat and barley. We have recently isolated the first two resistance genes against the fungal diseases leaf rust and powdery mildew of wheat. We are now studying their activity and the evolution of resistance at the molecular level. 

The different projects conducted in the research group strongly depend on the use of genomic technologies as well as advanced bioinformatics. 

Research topics

  • Fungal disease resistance in cereals

  • Structure and evolution of plant genomes

  • Molecular basis of agronomically important traits

  • Root hair development

Interdisciplinary

  • Evolutionary genomics

  • Molecular Agronomy and Plant Breeding

  • Plant Pathology

Contact Person

Prof. Dr. Beat Keller

University of Zurich
Institute of Plant Biology
Website
bkeller-at-botinst.uzh.ch
+41 (0)44 634 82 30

eligible for PLANT FELLOWS

Recent publications

  • Title: Aegilops tauschii draft genome sequence reveals a gene repertoire for wheat adaptation
    Author(s): Jia, Jizeng; Zhao, Shancen; Kong, Xiuying; et al.
    Source: NATURE, 496 (7443): 91-95 APR 4 2013
    Document Type: Article (Details)
  • Title: Identification of QTL associated with durable adult plant resistance to stem rust race Ug99 in wheat cultivar 'Pavon 76'
    Author(s): Njau, P. N.; Bhavani, S.; Huerta-Espino, J.; et al.
    Source: EUPHYTICA, 190 (1): 33-44 MAR 2013
    Document Type: Article (Details)
  • Title: Recent emergence of the wheat Lr34 multi-pathogen resistance: insights from haplotype analysis in wheat, rice, sorghum and Aegilops tauschii
    Author(s): Krattinger, Simon G.; Jordan, David R.; Mace, Emma S.; et al.
    Source: THEORETICAL AND APPLIED GENETICS, 126 (3): 663-672 MAR 2013
    Document Type: Article (Details)
  • Title: Comparative analysis of genome composition in Triticeae reveals strong variation in transposable element dynamics and nucleotide diversity
    Author(s): Middleton, Christopher P.; Stein, Nils; Keller, Beat; et al.
    Source: PLANT JOURNAL, 73 (2): 347-356 JAN 2013
    Document Type: Article (Details)
  • Title: Hybridization and speciation
    Author(s): Abbott, R.; Albach, D.; Ansell, S.; et al.
    Source: JOURNAL OF EVOLUTIONARY BIOLOGY, 26 (2): 229-246 FEB 2013
    Document Type: Review (Details)