The cereal genomes: hidden treasures for evolutionary genomics and agronomy

Plant Molecular Biology

We are studying the genomes of the grass species wheat, barley and rice to analyze genome evolution in cereals. Plant genomes generally evolve much more rapidly than animal genomes and we want to understand  the underlying molecular mechanisms. These studies in evolutionary genomics have already given surprising results: for the genomic regions analyzed to date, we found complete restructuring of the intergenic regions within 1 to 3 million years, a much faster and dramatic evolution than previously assumed.

The wheat genome is very large (5x the size of the human genome) and complex. The knowledge on cereal genome structure is used in our group for the molecular isolation of agronomically important genes from wheat and barley. We have recently isolated the first two resistance genes against the fungal diseases leaf rust and powdery mildew of wheat. We are now studying their activity and the evolution of resistance at the molecular level. 

The different projects conducted in the research group strongly depend on the use of genomic technologies as well as advanced bioinformatics. 

Research topics

  • Fungal disease resistance in cereals

  • Structure and evolution of plant genomes

  • Molecular basis of agronomically important traits

  • Root hair development

Interdisciplinary

  • Evolutionary genomics

  • Molecular Agronomy and Plant Breeding

  • Plant Pathology

Contact Person

Prof. Dr. Beat Keller

University of Zurich
Institute of Plant Biology
Website
bkeller-at-botinst.unizh.ch
+41 (0)44 634 82 30

eligible for PLANT FELLOWS

Recent publications

  • Title: Comprehensive Functional Analyses of Expressed Sequence Tags in Common Wheat (Triticum aestivum)
    Author(s): Manickavelu, Alagu; Kawaura, Kanako; Oishi, Kazuko; et al.
    Source: DNA RESEARCH, 19 (2): 165-177 APR 2012
    Document type: Article (Details)
  • Title: Functional variability of the Lr34 durable resistance gene in transgenic wheat
    Author(s): Risk, Joanna M.; Selter, Liselotte L.; Krattinger, Simon G.; et al.
    Source: PLANT BIOTECHNOLOGY JOURNAL, 10 (4): 477-487 MAY 2012
    Document type: Article (Details)
  • Title: Transgenic Pm3 multilines of wheat show increased powdery mildew resistance in the field
    Author(s): Brunner, Susanne; Stirnweis, Daniel; Quijano, Carolina Diaz; et al.
    Source: PLANT BIOTECHNOLOGY JOURNAL, 10 (4): 398-409 MAY 2012
    Document type: Article (Details)
  • Title: Identification and mapping of two powdery mildew resistance genes in Triticum boeoticum L.
    Author(s): Chhuneja, Parveen; Kumar, Krishan; Stirnweis, Daniel; et al.
    Source: THEORETICAL AND APPLIED GENETICS, 124 (6): 1051-1058 APR 2012
    Document type: Article (Details)
  • Title: Ancient diversity of splicing motifs and protein surfaces in the wild emmer wheat (Triticum dicoccoides) LR10 coiled coil (CC) and leucine-rich repeat (LRR) domains
    Author(s): Sela, Hanan; Spiridon, Laurentiu N.; Petrescu, Andrei-Jose; et al.
    Source: MOLECULAR PLANT PATHOLOGY, 13 (3): 276-287 APR 2012
    Document type: Article (Details)