The molecular basis of plant growth & development

Molecular Genetics & Natural Genetic Variation

A central feature of plant development is the post-embryonic formation of the majority of plant organs in a reiterative fashion. This build up of organs continues until the plant dies and can last hundreds of years in long-lived plants, like certain trees. Thus the control of plant growth and the elaboration of plant form are central to plant development. Our research revolves around the genetic control of plant growth and development, and the underlying molecular mechanisms. We focus on genes that are responsible for modifying quantitative aspects of growth and morphology. We isolate such genes by exploiting natural genetic variation, for instance as observed in wild Arabidopsis thaliana strains. Arabidopsis is also our model of choice to characterize the cell biological and biochemical functions of the respective proteins. We are particularly interested in genes that determine the growth rate and architecture of the root system, as well as genes that determine the rate of secondary growth, i.e. the thickening of stems. We also investigate the molecular evolutionary aspects of those genes and in their role in other species, with a focus on the monocotyledon model, Brachypodium.

Research topics

  • Natural genetic variation

  • Root system growth & architecture

  • Secondary growth

  • Plant hormone pathways

Interdisciplinary

  • Process modeling of root growth (in collaboration with Prof. Richard Smith, Bern; Dr. Ioannis Xenarios, SIB)

  • Bioinformatics approaches (collaboration with Dr. Ioannis Xenarios, SIB)

Contact Person

Prof. Dr. Christian Hardtke

University of Lausanne
Department of Plant Molecular Biology
Website
christian.hardtke-at-unil.ch
+41 (0)21 692 42 51


Recent publications

  • Title: Natural genetic variation of root system architecture from Arabidopsis to Brachypodium: towards adaptive value
    Author(s): Pacheco-Villalobos, David; Hardtke, Christian S.
    Source: PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES, 367 (1595): 1552-1558 JUN 5 2012
    Document type: Review (Details)
  • Title: Positional Information by Differential Endocytosis Splits Auxin Response to Drive Arabidopsis Root Meristem Growth
    Author(s): Santuari, Luca; Scacchi, Emanuele; Rodriguez-Villalon, Antia; et al.
    Source: CURRENT BIOLOGY, 21 (22): 1918-1923 NOV 22 2011
    Document type: Article (Details)
  • Mobile Gibberellin Directly Stimulates Arabidopsis Hypocotyl Xylem Expansion
    Ragni, L; Nieminen, K; Pacheco-Villalobos, D; et al.
    PLANT CELL 23 (4): 1322-1336 APR 2011 (Details)
  • Hormone Signalling Crosstalk in Plant Growth Regulation
    Depuydt, S; Hardtke, CS
    CURRENT BIOLOGY 21 (9): R365-R373 Sp. Iss. SI MAY 10 2011 (Details)
  • A qualitative continuous model of cellular auxin and brassinosteroid signaling and their crosstalk
    Sankar, M; Osmont, KS; Rolcik, J; et al.
    BIOINFORMATICS 27 (10): 1404-1412 MAY 15 2011 (Details)